Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109305 | 0.90 | MET (0.69) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL30948862 | 0.90 | MET (0.69) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29314899 | 0.87 | MET (0.48) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29314897 | 0.87 | MET (0.54) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29314924 | 0.87 | MET (0.52) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29314878 | 0.84 | MET (0.49) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL22109378 | 0.81 | MET (0.67) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL22109373 | 0.81 | MET (0.64) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL29314927 | 0.79 | MET (0.56) | METPDE3BPDE3APDE4CPDE4D | |
| SCHEMBL22109390 | 0.78 | MET (0.75) | METPDE3BPDE3ACYP2C9PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |