Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 12/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317734 | 0.84 | MET (0.43) | METATRKLKB1KLK1ACVR1 | |
| SCHEMBL29314805 | 0.80 | LDHB (0.48) | METATRACACBADORA2A | |
| SCHEMBL29314794 | 0.80 | MET (0.39) | METATRACVR1 | |
| SCHEMBL29314946 | 0.75 | MET (0.45) | MET | |
| SCHEMBL29314897 | 0.74 | MET (0.54) | MET | |
| SCHEMBL29317084 | 0.73 | MET (0.43) | METATRKLKB1KLK1ACVR1 | |
| SCHEMBL29314985 | 0.73 | MET (0.40) | METATRADORA2A | |
| SCHEMBL29317711 | 0.72 | MET (0.41) | METATRKLKB1KLK1ACVR1 | |
| SCHEMBL22109363 | 0.72 | MET (0.64) | MET | |
| SCHEMBL22109200 | 0.72 | ATR (0.39) | METATRADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |