Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314805 | 0.82 | LDHB (0.48) | METADORA2AATRCLK1LDHA | |
| SCHEMBL29315062 | 0.79 | MET (0.41) | METATRSYKHDAC1CDKL5 | |
| SCHEMBL29314644 | 0.77 | LDHA (0.43) | METHDAC6ATRSYKLDHA | |
| SCHEMBL29317734 | 0.76 | MET (0.43) | METHDAC6ATRCDKL5 | |
| SCHEMBL29314988 | 0.75 | MET (0.49) | MET | |
| SCHEMBL29315639 | 0.74 | LDHA (0.44) | METATRSYKLDHALDHB | |
| SCHEMBL29314890 | 0.73 | MET (0.39) | METADORA2AATR | |
| SCHEMBL22109175 | 0.73 | MET (0.52) | MET | |
| SCHEMBL29314116 | 0.72 | MET (0.41) | METHDAC6ATRSYKLDHA | |
| SCHEMBL29315036 | 0.72 | ADORA2A (0.33) | METADORA2AHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |