Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 13/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009155 | 1.00 | POLQ (0.38) | POLQSCN8ASCN10AFFAR4TACR1 | |
| SCHEMBL31009145 | 0.84 | POLQ (0.44) | POLQSCN8ASCN10AFFAR4 | |
| SCHEMBL29314474 | 0.84 | POLQ (0.44) | POLQSCN8ASCN10AFFAR4 | |
| SCHEMBL31009165 | 0.82 | POLQ (0.46) | POLQSCN8ASCN10AFFAR4 | |
| SCHEMBL31009196 | 0.81 | POLQ (0.35) | POLQTACR1 | |
| SCHEMBL29315670 | 0.81 | POLQ (0.35) | POLQTACR1 | |
| SCHEMBL29313852 | 0.74 | POLQ (0.41) | POLQSCN8ASCN10ATACR1 | |
| SCHEMBL29314303 | 0.72 | POLQ (0.33) | POLQSCN8ASCN10AFFAR4TACR1 | |
| SCHEMBL29313609 | 0.71 | POLQ (0.40) | POLQFFAR4 | |
| SCHEMBL29313706 | 0.69 | POLQ (0.35) | POLQTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |