Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29321466 | 0.99 | TSHR (0.52) | TSHRHSD17B10ALDH1A1CYP3A4MMP13 | |
| SCHEMBL13220802 | 0.99 | TSHR (0.52) | TSHRHSD17B10ALDH1A1CYP3A4MMP13 | |
| SCHEMBL2619036 | 0.99 | TSHR (0.52) | TSHRHSD17B10ALDH1A1CYP3A4MMP13 | |
| SCHEMBL21389608 | 0.99 | TSHR (0.52) | TSHRHSD17B10ALDH1A1CYP3A4MMP13 | |
| SCHEMBL29321446 | 0.96 | TSHR (0.48) | TSHRHSD17B10ALDH1A1CYP3A4MMP13 | |
| SCHEMBL29316074 | 0.91 | MMP13 (0.47) | TSHRHSD17B10ALDH1A1MMP13MMP12 | |
| SCHEMBL21242234 | 0.87 | TSHR (0.61) | TSHRHSD17B10ALDH1A1CYP3A4THRB | |
| SCHEMBL21242530 | 0.87 | TSHR (0.61) | TSHRHSD17B10ALDH1A1CYP3A4THRB | |
| SCHEMBL13506252 | 0.87 | TSHR (0.61) | TSHRHSD17B10ALDH1A1CYP3A4THRB | |
| SCHEMBL5961806 | 0.86 | MMP3 (0.58) | TSHRALDH1A1CYP3A4MMP13THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |