SCHEMBL5961806

SCHEMBL5961806

C=CC(=O)OCCCCOc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 5/20 0.58
MMP2 P08253 7/20 0.57
HDAC1 Q13547 1/20 0.56
HDAC2 Q92769 1/20 0.56
MMP1 P03956 1/20 0.53
MMP9 P14780 1/20 0.53
MMP13 P45452 1/20 0.53
THRB P10828 1/20 0.52
ALDH1A1 P00352 2/20 0.49
TSHR P16473 2/20 0.49
CYP3A4 P08684 1/20 0.49
HRH3 Q9Y5N1 6/20 0.48
HRH2 P25021 5/20 0.48
HRH1 P35367 5/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8939373 0.99 HDAC1 (0.59) MMP3MMP2HDAC1HDAC2MMP1
SCHEMBL8939317 0.99 HDAC1 (0.59) MMP3MMP2HDAC1HDAC2MMP1
SCHEMBL8939360 0.99 HDAC1 (0.59) MMP3MMP2HDAC1HDAC2MMP1
SCHEMBL7590582 0.99 HDAC1 (0.59) MMP3MMP2HDAC1HDAC2MMP1
SCHEMBL103263 0.99 HDAC1 (0.59) MMP3MMP2HDAC1HDAC2MMP1
SCHEMBL8939353 0.99 HDAC1 (0.59) MMP3MMP2HDAC1HDAC2MMP1
SCHEMBL8939366 0.99 HDAC1 (0.59) MMP3MMP2HDAC1HDAC2MMP1
SCHEMBL8939370 0.99 HDAC1 (0.59) MMP3MMP2HDAC1HDAC2MMP1
SCHEMBL4331061 0.97 MMP2 (0.57) MMP3MMP2HDAC1HDAC2MMP1
SCHEMBL2241855 0.96 THRB (0.56) MMP3MMP2HDAC1HDAC2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115301082-A Nanoscale microporous filter membrane, preparation method and application thereof 上海先认新材料合伙企业(有限合伙) 2022-11-08 CN claimed
EP-4689003-A1 METHOD University of Leeds (GB) 2026-02-11 EP disclosed
WO-2024201014-A1 METHOD UNIVERSITY OF LEEDS (GB) 2024-10-03 WO disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 US disclosed
EP-4299283-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE Tosoh Corporation (JP) 2024-01-03 EP disclosed
US-20160047963-A1 POLARIZING PLATE AND METHOD FOR PRODUCING SAME, AND TRANSFER MATERIAL FUJIFILM CORPORATION (JP) 2016-02-18 US disclosed
US-20160047963-A1 POLARIZING PLATE AND METHOD FOR PRODUCING SAME, AND TRANSFER MATERIAL FUJIFILM CORPORATION (JP) 2016-02-18 US disclosed
US-20150125631-A1 OPTICAL FILM AND DISPLAY DEVICE USING THE SAME (As Amended) LG CHEM, LTD. (KR) 2015-05-07 US disclosed
US-20150125631-A1 OPTICAL FILM AND DISPLAY DEVICE USING THE SAME (As Amended) LG CHEM, LTD. (KR) 2015-05-07 US disclosed
US-8168734-B2 Lateral alpha-substituted acrylate compound and polymer thereof JNC CORPORATION (JP) 2012-05-01 US disclosed
US-20110144293-A1 LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF CHISSO CORPORATION (JP) 2011-06-16 US disclosed
US-7919648-B2 Lateral α-substituted acrylate compound and polymer thereof CHISSO CORPORATION (JP) 2011-04-05 US disclosed
US-7410677-B2 Organosilicon compound-containing polymerizable liquid-crystal composition CHISSO CORPORATION (JP) 2008-08-12 US disclosed
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof CHISSO CORPORATION 2007-06-14 US disclosed
US-7157124-B2 Polymerizable compounds and their polymers CHISSO PETROCHEMICAL CORPORATION (JP) 2007-01-02 US disclosed
EP-0955348-B1 LIQUID-CRYSTAL COMPOSITION AND POLYMERIC LIQUID CRYSTAL OBTAINED BY POLYMERIZING THE SAME ASAHI GLASS CO LTD (JP) 2002-10-23 EP disclosed
US-6180028-B1 ACRYLATED ESTERS ASAHI GLASS COMPANY LTD. (JP) 2001-01-30 US disclosed
EP-0955348-A1 LIQUID-CRYSTAL COMPOSITION AND POLYMERIC LIQUID CRYSTAL OBTAINED BY POLYMERIZING THE SAME Asahi Glass Company Ltd. (JP) 1999-11-10 EP disclosed
US-5498363-A Electrorheological fluid AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144293-A1 LATERAL ALPHA-SUBSTITUTED ACRYLATE COMPOUND AND POLYMER THEREOF LEF1, AFF1, CNKSR1 MMP3 2617/4885MMP2 4513/4885HDAC1 1597/4885
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof AFF1, CNKSR1, LEF1 MMP3 3127/4885MMP2 4565/4885HDAC1 1513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.