Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29316380 | 0.97 | LMNA (0.44) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL1933322 | 0.87 | TSHR (0.49) | TSHRCYP3A4TP53ALDH1A1LMNA | |
| SCHEMBL4594786 | 0.87 | THRB (0.44) | TSHRCYP3A4TP53ALDH1A1THRB | |
| SCHEMBL26977459 | 0.87 | TSHR (0.53) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL29316353 | 0.86 | TSHR (0.51) | TSHRCYP3A4TP53ALDH1A1LMNA | |
| SCHEMBL13332086 | 0.84 | TSHR (0.45) | TSHRCYP3A4TP53ALDH1A1LMNA | |
| SCHEMBL12285575 | 0.83 | ALDH1A1 (0.51) | TSHRCYP3A4TP53ALDH1A1THRB | |
| SCHEMBL5968386 | 0.83 | ALDH1A1 (0.51) | TSHRCYP3A4TP53ALDH1A1THRB | |
| SCHEMBL27134336 | 0.82 | TSHR (0.48) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL7115632 | 0.80 | TSHR (0.62) | TSHRCYP3A4MAPK1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |