Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314831 | 0.89 | POLQ (0.42) | POLQCES2TSHRLMNA | |
| SCHEMBL29315012 | 0.79 | POLQ (0.41) | POLQLMNA | |
| SCHEMBL29314384 | 0.75 | POLQ (0.52) | POLQTSHRLMNA | |
| SCHEMBL29315955 | 0.69 | POLQ (0.36) | POLQ | |
| SCHEMBL29315103 | 0.68 | POLQ (0.37) | POLQ | |
| SCHEMBL29314388 | 0.66 | POLQ (0.50) | POLQTSHRLMNA | |
| SCHEMBL19105242 | 0.64 | NOTUM (0.36) | CES2LMNA | |
| SCHEMBL30847733 | 0.64 | TACR1 (0.44) | POLQ | |
| SCHEMBL19105211 | 0.64 | AKT1 (0.34) | CES2 | |
| SCHEMBL30847596 | 0.64 | POLQ (0.50) | POLQTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |