Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13065450 | 0.91 | PIK3CD (0.47) | PIK3CDHSD17B10EPHX2EPHX1MEN1 | |
| SCHEMBL17522138 | 0.84 | PIK3CD (0.43) | PIK3CDHSD17B10DPP8DPP7EPHX2 | |
| SCHEMBL17522201 | 0.84 | PIK3CD (0.43) | PIK3CDHSD17B10DPP8DPP7EPHX2 | |
| SCHEMBL17522199 | 0.84 | PIK3CD (0.43) | PIK3CDHSD17B10DPP8DPP7EPHX2 | |
| SCHEMBL18897210 | 0.81 | GNAI3 (0.40) | DPP8DPP7EPHX2EPHX1BRD4 | |
| SCHEMBL19277102 | 0.81 | AKR1C3 (0.45) | EPHX2EPHX1BRD4 | |
| SCHEMBL13509613 | 0.81 | GNAI3 (0.40) | DPP8DPP7EPHX2EPHX1BRD4 | |
| SCHEMBL22968035 | 0.81 | AKR1C3 (0.45) | EPHX2EPHX1BRD4 | |
| SCHEMBL27383617 | 0.81 | AKR1C3 (0.45) | EPHX2EPHX1BRD4 | |
| SCHEMBL13251384 | 0.81 | PIK3CD (0.44) | PIK3CDHSD17B10EPHX2EPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | PIK3CD 3368/4885HSD17B10 1263/4885DPP8 2072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.