Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22520701 | 0.92 | CACNA2D1 (0.36) | CYP2D6CYP1A2NCF1CACNA2D1CACNA1B | |
| SCHEMBL27013290 | 0.89 | HRH3 (0.33) | CYP2D6CYP1A2NCF1HRH3 | |
| SCHEMBL22520604 | 0.87 | HRH3 (0.36) | CYP2D6TLR9TLR8TLR7SMN1; SMN2 | |
| SCHEMBL25565564 | 0.85 | CACNA2D1 (0.37) | CYP2D6CYP1A2NCF1CACNA2D1CACNA1B | |
| SCHEMBL27323574 | 0.85 | CACNA2D1 (0.37) | CYP2D6CYP1A2NCF1CACNA2D1CACNA1B | |
| SCHEMBL23598175 | 0.85 | CACNA2D1 (0.37) | CYP2D6CYP1A2NCF1CACNA2D1CACNA1B | |
| SCHEMBL24480642 | 0.85 | NCF1 (0.41) | CYP2D6CYP1A2NCF1CACNA2D1CACNA1B | |
| SCHEMBL27307184 | 0.83 | OPRM1 (0.38) | NCF1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL22520762 | 0.81 | ACHE (0.35) | CYP2D6TLR9TLR8TLR7SMN1; SMN2 | |
| SCHEMBL24475331 | 0.80 | CYP2D6 (0.33) | CYP2D6SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |