Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19113479 | 0.86 | SIGMAR1 (0.51) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL3046018 | 0.85 | SLC6A2 (0.57) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 | |
| Hydrochloric Acid SCHEMBL16702960 | 0.83 | SLC6A2 (0.55) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL28406689 | 0.81 | SIGMAR1 (0.77) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL13885045 | 0.81 | MAOB (0.60) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL2474864 | 0.81 | MAOB (0.60) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL29137651 | 0.79 | SIGMAR1 (0.50) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL22398926 | 0.78 | SIGMAR1 (0.57) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL13994249 | 0.77 | ADRA2B (0.46) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 | |
| Hydrochloric Acid SCHEMBL10619477 | 0.77 | SIGMAR1 (0.56) | SIGMAR1ADRA2BADRA2CADRA1AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239805-A1 | AZA-YANG CYCLIZATION-BUCHNER AROMATIC RING EXPANSION: COLLECTIVE SYNTHESIS OF CYCLOHEPTATRIENE-CONTAINING AZETIDINE LACTONES | UNIVERSITY OF KANSAS | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239805-A1 | AZA-YANG CYCLIZATION-BUCHNER AROMATIC RING EXPANSION: COLLECTIVE SYNTHESIS OF CYCLOHEPTATRIENE-CONTAINING AZETIDINE LACTONES | AZI2, NISCH, TET2 | SIGMAR1 3477/4885ADRA2B 1046/4885ADRA2C 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.