Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228204 | 0.86 | TAAR1 (0.43) | OPRK1SLC6A2MAOBTAAR1 | |
| SCHEMBL3046018 | 0.82 | SLC6A2 (0.57) | ADRA2BHTR2AKCNH2ADRA2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL16702960 | 0.81 | SLC6A2 (0.55) | ADRA2BHTR2AKCNH2ADRA2ASIGMAR1 | |
| SCHEMBL13994397 | 0.79 | PGR (0.47) | ADRA2BHTR2AKCNH2ADRA2APGR | |
| SCHEMBL19113479 | 0.77 | SIGMAR1 (0.51) | ADRA2BHTR2AKCNH2ADRA2ASIGMAR1 | |
| SCHEMBL29317137 | 0.77 | SIGMAR1 (0.51) | ADRA2BHTR2AKCNH2ADRA2ASIGMAR1 | |
| SCHEMBL29137651 | 0.76 | SIGMAR1 (0.50) | ADRA2BHTR2AKCNH2ADRA2ASIGMAR1 | |
| Isobutylbenzene SCHEMBL28202538 | 0.75 | PTGS1 (0.52) | HTR2ANPC1RAB9ACYP1A2TRPA1 | |
| SCHEMBL20482051 | 0.75 | SIGMAR1 (0.46) | ADRA2BHTR2AKCNH2ADRA2APGR | |
| SCHEMBL23157196 | 0.73 | ACACB (0.59) | ADRA2BHTR2AKCNH2ADRA2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462592-B2 | Compositions and methods for polynucleotide delivery | NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) | 2008-12-09 | — | — | US | disclosed |