Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 2/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856130 | 0.90 | ACHE (0.46) | ACHEGBA1KDM4EPOLBGNAO1 | |
| SCHEMBL25027099 | 0.88 | ACHE (0.40) | ACHEGBA1KDM4EPOLBGNAO1 | |
| SCHEMBL25027129 | 0.87 | ACHE (0.53) | ACHEGBA1KDM4EPOLBGNAO1 | |
| SCHEMBL24480693 | 0.86 | GBA1 (0.47) | GBA1GNAO1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL24480843 | 0.83 | GBA1 (0.43) | ACHEGBA1GNAO1CACNA2D1CACNA1B | |
| SCHEMBL24480701 | 0.83 | GBA1 (0.40) | GBA1GNAO1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL13661595 | 0.82 | ACHE (0.64) | ACHEGBA1GNAO1CACNA2D1CACNA1B | |
| SCHEMBL24480367 | 0.82 | ACHE (0.40) | ACHEKDM4EPOLB | |
| SCHEMBL24481166 | 0.82 | ACHE (0.40) | ACHEKDM4EPOLB | |
| SCHEMBL24481341 | 0.81 | ACHE (0.46) | ACHEKDM4EPOLBCACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |