Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29317185 | 0.90 | ACHE (0.44) | ACHEGBA1KDM4EPOLBGNAO1 | |
| SCHEMBL25027129 | 0.90 | ACHE (0.53) | ACHEGBA1KDM4EPOLBGNAO1 | |
| SCHEMBL24480695 | 0.86 | ACHE (0.43) | ACHEKDM4EPOLBCARM1PRMT6 | |
| SCHEMBL25565964 | 0.83 | ACHE (0.50) | ACHEGBA1KDM4EGNAO1CARM1 | |
| SCHEMBL24718636 | 0.83 | CHRM5 (0.46) | ACHEGBA1GNAO1CACNA2D1CACNA1B | |
| SCHEMBL13661595 | 0.83 | ACHE (0.64) | ACHEGBA1GNAO1CARM1PRMT6 | |
| SCHEMBL24480687 | 0.83 | ACHE (0.47) | ACHEKDM4EPOLBCARM1PRMT6 | |
| SCHEMBL25027099 | 0.82 | ACHE (0.40) | ACHEGBA1KDM4EPOLBGNAO1 | |
| Hydrochloric Acid SCHEMBL22033207 | 0.81 | ACHE (0.62) | ACHEGBA1GNAO1CARM1PRMT6 | |
| SCHEMBL25856132 | 0.79 | ACHE (0.43) | ACHEKDM4EPOLBCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |