Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298174 | 0.82 | GRM7 (0.41) | MTNR1AMTNR1B | |
| SCHEMBL16823636 | 0.81 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL11621421 | 0.77 | GAA (0.50) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL1775223 | 0.74 | TSHR (0.33) | GAAITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL12610368 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL881106 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL29332740 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562992 | 0.70 | EPHX2 (0.43) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8568797 | 0.69 | MTNR1A (0.39) | MTNR1AMTNR1BEPHX2ITGB3ITGAV | |
| SCHEMBL924219 | 0.69 | GAA (0.54) | MTNR1AMTNR1BEPHX2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |