Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562992 | 0.88 | EPHX2 (0.43) | MTNR1AMTNR1BEPHX2BRD4MEN1 | |
| SCHEMBL8569787 | 0.78 | EPHX2 (0.42) | MTNR1AMTNR1BEPHX2BRD4MEN1 | |
| SCHEMBL8569796 | 0.78 | EPHX2 (0.42) | MTNR1AMTNR1BEPHX2BRD4MEN1 | |
| SCHEMBL12610368 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BEPHX2BRD4MEN1 | |
| SCHEMBL881106 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BEPHX2BRD4MEN1 | |
| SCHEMBL29332740 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BEPHX2BRD4MEN1 | |
| SCHEMBL7415028 | 0.70 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2BRD4MEN1 | |
| SCHEMBL7415031 | 0.70 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2BRD4MEN1 | |
| SCHEMBL2931724 | 0.69 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2BRD4MEN1 | |
| SCHEMBL8568802 | 0.69 | MTNR1A (0.48) | MTNR1AMTNR1BEPHX2BRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |