SCHEMBL29317294

SCHEMBL29317294

CCC1OC(n2cc(C)c(=O)[nH]c2=O)CC1OC(=O)COC(=O)c1cc(C)c(C)c(C)c1

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.56
TK1 P04183 2/20 0.46
TK2 O00142 1/20 0.45
ABCG2 Q9UNQ0 3/20 0.45
ABCB1 P08183 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29317296 0.93 RNASE1 (0.66) RNASE1TK1TK2
SCHEMBL29317378 0.91 RNASE1 (0.55) RNASE1TK1TK2ABCG2ABCB1
SCHEMBL29317380 0.85 RNASE1 (0.54) RNASE1TK1TK2ABCG2ABCB1
SCHEMBL23394628 0.84 RNASE1 (0.64) RNASE1TK1
SCHEMBL29317377 0.84 RNASE1 (0.64) RNASE1TK1TK2
SCHEMBL23914467 0.82 RNASE1 (0.61) RNASE1TK1
SCHEMBL15498284 0.81 RNASE1 (0.63) RNASE1TK1
SCHEMBL12932156 0.81 RNASE1 (0.63) RNASE1TK1
SCHEMBL15498298 0.81 RNASE1 (0.63) RNASE1TK1
SCHEMBL15187886 0.81 RNASE1 (0.63) RNASE1TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT RNASE1 83/4885TK1 236/4885TK2 128/4885
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT RNASE1 83/4885TK1 236/4885TK2 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.