Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.61 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | TK1 | P04183 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29319148 | 0.92 | RNASE1 (0.60) | RNASE1TOP2ATK1LMNATSHR | |
| SCHEMBL29317296 | 0.89 | RNASE1 (0.66) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL23394628 | 0.88 | RNASE1 (0.64) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL23387098 | 0.86 | RNASE1 (0.56) | RNASE1TK1SLC6A2 | |
| SCHEMBL23914022 | 0.85 | RNASE1 (0.57) | RNASE1TOP2ATK1LMNATSHR | |
| SCHEMBL21078683 | 0.85 | RNASE1 (0.56) | RNASE1TOP2ATK1LMNATSHR | |
| SCHEMBL8432697 | 0.83 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL8432694 | 0.83 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL29317294 | 0.82 | RNASE1 (0.56) | RNASE1TK1 | |
| SCHEMBL28535589 | 0.82 | RNASE1 (0.57) | RNASE1TK1LMNATSHRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239834-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | FUJIMOTO CHEMICALS CO., LTD., (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20210317159-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | FUJIMOTO CHEMICALS CO., LTD. (JP) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239834-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | ROS1, POLN, RNMT | RNASE1 83/4885TOP2A 1092/4885TK1 236/4885 |
| US-20210317159-A1 | ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS | ROS1, POLN, RNMT | RNASE1 83/4885TOP2A 1092/4885TK1 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.