Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20848140 | 0.76 | — | — | |
| SCHEMBL21417396 | 0.69 | — | — | |
| SCHEMBL21118211 | 0.68 | — | — | |
| SCHEMBL28698674 | 0.67 | — | — | |
| SCHEMBL24340138 | 0.65 | — | — | |
| SCHEMBL14423706 | 0.64 | — | — | |
| SCHEMBL14957090 | 0.63 | — | — | |
| SCHEMBL8991460 | 0.63 | LMNA (0.38) | LMNA | |
| SCHEMBL9482451 | 0.62 | — | — | |
| SCHEMBL22955056 | 0.62 | DDAH1 (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031547-B1 | PLASMA KALLIKREIN INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-17 | — | — | EP | disclosed |