SCHEMBL29319682

SCHEMBL29319682

Oc1cc(O)cc(-c2cc(F)cc(F)c2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.67
CA1 P00915 1/20 0.67
CA9 Q16790 1/20 0.67
ABL1 P00519 3/20 0.50
ABCB1 P08183 3/20 0.50
BCR P11274 3/20 0.50
BACE1 P56817 1/20 0.47
HSD17B1 P14061 3/20 0.47
HSD17B2 P37059 3/20 0.47
SIRT1 Q96EB6 2/20 0.44
NQO1 P15559 1/20 0.43
HCAR1 Q9BXC0 1/20 0.41
PTGS1 P23219 1/20 0.39
ESR2 Q92731 1/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9008914 0.94 CA12 (0.77) CA12CA1CA9ABL1ABCB1
SCHEMBL29319825 0.83 ALDH1A1 (0.52) CA12CA1CA9ABL1ABCB1
SCHEMBL156265 0.81
SCHEMBL972239 0.81
SCHEMBL19665087 0.80 CA12 (0.50) CA12CA1CA9SIRT1CES2
SCHEMBL337732 0.80 BACE1 (0.73) CA12CA1CA9ABL1ABCB1
SCHEMBL9008923 0.79 HSD17B1 (0.55) CA12CA1CA9ABL1ABCB1
SCHEMBL29319890 0.79 RXRA (0.50) CA12CA1CA9ABL1ABCB1
SCHEMBL412217 0.78 ESR1 (0.65) CA12CA1CA9ABL1ABCB1
SCHEMBL6068001 0.78 ABL1 (0.67) CA12CA1CA9ABL1ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239931-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CHEMOURS COMPANY FC, LLC, THE 2024-07-18 US disclosed
US-20240239931-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CHEMOURS COMPANY FC, LLC, THE 2024-07-18 US disclosed