SCHEMBL29319688

SCHEMBL29319688

Cc1cccc(-c2cc(C)cc(O)c2)c1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.60
ABL1 P00519 1/20 0.52
ABCB1 P08183 1/20 0.52
BCR P11274 1/20 0.52
HSD17B1 P14061 4/20 0.52
HSD17B2 P37059 4/20 0.52
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
AKR1C2 P52895 1/20 0.47
AKR1C1 Q04828 1/20 0.47
DHODH Q02127 1/20 0.45
QPCT Q16769 1/20 0.43
MEN1 O00255 1/20 0.43
ESR1 P03372 1/20 0.43
KMT2A Q03164 1/20 0.43
PTPN5 P54829 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25014571 0.96 ABL1 (0.57) ACHEABL1ABCB1BCRHSD17B1
SCHEMBL25014572 0.96 ABL1 (0.57) ACHEABL1ABCB1BCRHSD17B1
SCHEMBL29319745 0.93 ABL1 (0.59) ACHEABL1ABCB1BCRHSD17B1
SCHEMBL18736378 0.91 ABL1 (0.63) ACHEABL1ABCB1BCRHSD17B1
SCHEMBL26135069 0.91 HSD17B1 (0.60) ACHEABL1ABCB1BCRHSD17B1
SCHEMBL1029701 0.86 ACHE (0.73) ACHEHSD17B1HSD17B2ALDH1A1CYP3A4
SCHEMBL30545101 0.86 ACHE (0.73) ACHEHSD17B1HSD17B2ALDH1A1CYP3A4
SCHEMBL22861278 0.84 HSD17B1 (0.62) ACHEABL1ABCB1BCRHSD17B1
SCHEMBL3361811 0.84 ALDH1A1 (0.52) ACHEABL1ABCB1BCRHSD17B1
SCHEMBL8264985 0.84 ESR2 (0.48) ACHEABL1ABCB1BCRHSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239931-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CHEMOURS COMPANY FC, LLC, THE 2024-07-18 US disclosed