Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 10/20 | 0.71 |
| ▸ | CTNNB1 | P35222 | 10/20 | 0.71 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030443 | 0.83 | BCL9 (1.00) | BCL9CTNNB1PPARA | |
| SCHEMBL4033030 | 0.83 | BCL9 (1.00) | BCL9CTNNB1PPARA | |
| SCHEMBL4030436 | 0.83 | BCL9 (1.00) | BCL9CTNNB1PPARA | |
| SCHEMBL29319669 | 0.77 | PPARA (0.66) | BCL9CTNNB1PPARASMN1; SMN2DRD2 | |
| SCHEMBL29322336 | 0.72 | KMT2A (0.54) | BCL9CTNNB1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL27616063 | 0.71 | PPARA (0.69) | BCL9CTNNB1PPARADRD2DRD3 | |
| SCHEMBL27634993 | 0.71 | PPARA (0.69) | BCL9CTNNB1PPARADRD2DRD3 | |
| SCHEMBL27634943 | 0.71 | PPARA (0.69) | BCL9CTNNB1PPARADRD2DRD3 | |
| SCHEMBL4027843 | 0.71 | BCL9 (0.79) | BCL9CTNNB1PPARA | |
| SCHEMBL4035857 | 0.71 | BCL9 (0.79) | BCL9CTNNB1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |