Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30677754 | 0.83 | KMT2A (0.60) | KMT2AMEN1HRH3RAB9ASMN1; SMN2 | |
| SCHEMBL23252438 | 0.81 | KMT2A (0.55) | KMT2AMEN1HRH3RAB9AKDM4E | |
| SCHEMBL5217325 | 0.80 | KDM4E (0.68) | KMT2AMEN1HRH3SMN1; SMN2ALDH1A1 | |
| SCHEMBL6559744 | 0.80 | KDM4E (0.68) | KMT2AMEN1HRH3SMN1; SMN2ALDH1A1 | |
| SCHEMBL3126965 | 0.78 | NPC1 (0.57) | KMT2AMEN1HRH3RAB9ASMN1; SMN2 | |
| SCHEMBL8225709 | 0.78 | MEN1 (0.55) | KMT2AMEN1HRH3ALDH1A1KDM4E | |
| SCHEMBL4197501 | 0.78 | KDM4E (0.69) | KMT2AMEN1HRH3SMN1; SMN2ALDH1A1 | |
| SCHEMBL5146467 | 0.77 | TPSAB1 (0.50) | KMT2AMEN1HRH3RAB9AKDM4E | |
| SCHEMBL29322550 | 0.77 | SMN1; SMN2 (0.64) | KMT2AMEN1HRH3RAB9ASMN1; SMN2 | |
| SCHEMBL5740992 | 0.77 | HRH3 (0.59) | KMT2AMEN1HRH3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |