SCHEMBL29320313

SCHEMBL29320313

Oc1cc(O)cc(-c2ccc(C(F)(F)F)cc2C(F)(F)F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.46
PTGS1 P23219 4/20 0.44
KIF11 P52732 2/20 0.44
ALOX5AP P20292 2/20 0.43
FEN1 P39748 2/20 0.43
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
EDNRB P24530 1/20 0.40
EDNRA P25101 1/20 0.40
CYP2C9 P11712 1/20 0.39
SCN9A Q15858 1/20 0.39
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
ABCC8 Q09428 1/20 0.38
KCNJ11 Q14654 1/20 0.38
ABL1 P00519 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24017166 0.82 CES2 (0.46) CES2KIF11ALOX5APFEN1EDNRB
SCHEMBL29319798 0.80 AKR1C3 (0.46) KIF11HSD17B1HSD17B2GLAPOLB
SCHEMBL28676412 0.80 TSHR (0.56) CES2KIF11ALOX5APFEN1EDNRB
SCHEMBL30600399 0.78 TSHR (0.52) CES2KIF11ALOX5APFEN1EDNRB
SCHEMBL26375550 0.78 AKR1C3 (0.47) CES2KIF11ALOX5APFEN1EDNRB
SCHEMBL10026559 0.77 CA1 (0.47) CES2ALOX5APFEN1EDNRBEDNRA
SCHEMBL4781603 0.77 KIF11 (0.54) CES2KIF11ALOX5APFEN1EDNRB
SCHEMBL28972411 0.77 ABL1 (0.53) SCN9AABL1ABCB1BCR
SCHEMBL26375459 0.75 AKR1C3 (0.45) CES2KIF11ALOX5APFEN1EDNRB
SCHEMBL24017193 0.74 CES2 (0.46) CES2PTGS1KIF11ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239931-A1 FLUORINATED RESORCINOL AND HYDROQUINONE ANALOGS AS CURING AGENTS FOR FLUOROELASTOMERS CHEMOURS COMPANY FC, LLC, THE 2024-07-18 US disclosed