SCHEMBL24017166

SCHEMBL24017166

FC(F)(F)c1cc(-c2ccc(C(F)(F)F)cc2C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.46
ALOX5AP P20292 1/20 0.46
FEN1 P39748 1/20 0.46
GLA P06280 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 1/20 0.42
EDNRB P24530 1/20 0.40
EDNRA P25101 1/20 0.40
ABCC8 Q09428 1/20 0.40
KCNJ11 Q14654 1/20 0.40
RXRA P19793 2/20 0.39
RXRB P28702 2/20 0.39
RXRG P48443 2/20 0.39
GPR3 P46089 1/20 0.39
AKR1C3 P42330 3/20 0.39
AKR1C2 P52895 3/20 0.39
AKR1C1 Q04828 1/20 0.39
CYP2C9 P11712 1/20 0.39
SCN9A Q15858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15498900 0.89 SCN9A (0.42) CES2ALOX5APFEN1EDNRBEDNRA
SCHEMBL26375459 0.87 AKR1C3 (0.45) CES2ALOX5APFEN1GLAPOLB
SCHEMBL24017179 0.86 SCN9A (0.44) CES2ALOX5APFEN1EDNRBEDNRA
SCHEMBL28676412 0.84 TSHR (0.56) CES2ALOX5APFEN1GLAPOLB
SCHEMBL24017184 0.83 PDE3B (0.39) CES2ALOX5APFEN1GLAPOLB
SCHEMBL24212697 0.83 ALOX5AP (0.39) CES2ALOX5APFEN1GLAPOLB
SCHEMBL21766570 0.83 ALOX5AP (0.41) CES2ALOX5APFEN1AKR1C3AKR1C2
SCHEMBL29320313 0.82 CES2 (0.46) CES2ALOX5APFEN1GLAPOLB
SCHEMBL26375483 0.82 AKR1C3 (0.43) GLAPOLBGAATSHRRXRA
SCHEMBL30600399 0.82 TSHR (0.52) CES2ALOX5APFEN1GLAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11858952-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-01-02 US disclosed
US-20210347790-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME LG CHEM, LTD. (KR) 2021-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210347790-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME BLVRB, CDYL, CRY1 CES2 344/4885ALOX5AP 2865/4885FEN1 2481/4885
US-11858952-B2 Compound and color conversion film comprising same BLVRB, CDYL, CRY1 CES2 344/4885ALOX5AP 2865/4885FEN1 2481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.