Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CDC25B | P30305 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23115218 | 0.84 | PKM (0.46) | PKMALDH1A1HSD17B10SMN1; SMN2TP53 | |
| SCHEMBL23117246 | 0.84 | PKM (0.46) | PKMALDH1A1SMN1; SMN2TP53MAPT | |
| SCHEMBL6839194 | 0.83 | PSMB5 (0.49) | PKMALDH1A1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL5473553 | 0.80 | KDM4E (0.49) | PKMALDH1A1SMN1; SMN2CDC25BKDM4E | |
| SCHEMBL3135580 | 0.77 | MAOB (0.56) | PKMALDH1A1HSD17B10SMN1; SMN2TP53 | |
| SCHEMBL7825337 | 0.76 | CHEK1 (0.44) | PKMCHEK1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL28137286 | 0.75 | CHEK1 (0.51) | PKMCHEK1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL29321733 | 0.75 | SMN1; SMN2 (0.52) | PKMCHEK1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL3142760 | 0.75 | ALDH1A1 (0.54) | PKMCHEK1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11224969 | 0.74 | CHEK1 (0.50) | PKMCHEK1ALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400499-A1 | GLUTARIMIDE COMPOUND AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |