Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828927 | 0.87 | ALDH1A1 (0.46) | CHEK1KDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL7816604 | 0.80 | GPR35 (0.43) | KDM4ELMNAALDH1A1PKMMAPT | |
| SCHEMBL23117350 | 0.77 | PLK1 (0.55) | KDM4ELMNAALDH1A1HSD17B10AHR | |
| SCHEMBL7826135 | 0.76 | ALDH1A1 (0.35) | KDM4EALDH1A1HSD17B10PKMNPC1 | |
| SCHEMBL29322303 | 0.76 | PKM (0.46) | CHEK1KDM4EALDH1A1HSD17B10AHR | |
| SCHEMBL7828330 | 0.75 | KMT2A (0.43) | KDM4ELMNAALDH1A1HSD17B10MAPT | |
| SCHEMBL7822767 | 0.75 | HPGD (0.42) | KDM4ELMNAALDH1A1HSD17B10PKM | |
| SCHEMBL29321733 | 0.75 | SMN1; SMN2 (0.52) | CHEK1LMNAALDH1A1HSD17B10PKM | |
| SCHEMBL28118721 | 0.74 | CHEK1 (0.50) | CHEK1KDM4ELMNAALDH1A1HSD17B10 | |
| SCHEMBL7816913 | 0.74 | NPC1 (0.45) | KDM4ELMNAALDH1A1HSD17B10AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-B1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |