Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23099952 | 0.83 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL524282 | 0.80 | KIF11 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL1491275 | 0.75 | HDAC1 (0.35) | HDAC1HDAC6 | |
| SCHEMBL465082 | 0.71 | KIF11 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL10842487 | 0.71 | KIF11 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL6411348 | 0.71 | NOTUM (0.32) | — | |
| SCHEMBL16127412 | 0.71 | AR (0.33) | — | |
| SCHEMBL14885993 | 0.70 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL29322468 | 0.70 | HDAC1 (0.32) | HDAC1HDAC6 | |
| 1,6-Hexanediol SCHEMBL18916857 | 0.68 | KIF11 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228512-A1 | ACYCLIC OXAZEPINE COMPOUNDS COMPRISING A 6-AZA MOIETY AND USES THEREOF | GENENTECH, INC. (US) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228512-A1 | ACYCLIC OXAZEPINE COMPOUNDS COMPRISING A 6-AZA MOIETY AND USES THEREOF | AZI2, HDAC5, HDAC4 | CYP11B1 1136/4885CYP11B2 744/4885HDAC1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.