SCHEMBL524282

SCHEMBL524282

Cc1c(F)cc(C(F)(F)F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.31
HSD11B1 P28845 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
MPL P40238 1/20 0.30
PDE2A O00408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL18916857 0.85 KIF11 (0.33) KIF11
SCHEMBL5074648 0.82
SCHEMBL10842487 0.81 KIF11 (0.31) KIF11HSD11B1CYP11B1CYP11B2MPL
SCHEMBL465082 0.81 KIF11 (0.34) KIF11HSD11B1CYP11B1CYP11B2MPL
SCHEMBL15892732 0.81 ALDH1A1 (0.34)
SCHEMBL29322467 0.80 CYP11B1 (0.31) CYP11B1CYP11B2
SCHEMBL17468322 0.77 CFTR (0.31)
SCHEMBL7905835 0.77 TP53 (0.35) HSD11B1
SCHEMBL3687267 0.77 KIF11 (0.34) KIF11
SCHEMBL30741240 0.77 KIF11 (0.34) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119261333-B PFA composite material laminated plate and preparation method thereof 上海森桓新材料科技有限公司 2025-03-11 CN claimed
CN-119261333-A PFA composite material laminated plate and preparation method thereof 上海森桓新材料科技有限公司 2025-01-07 CN claimed
CN-117229510-A Preparation method of hydrophobic oleophobic polysilsesquioxane spherical particles 浙江豪韵塑竹木材料有限公司 2023-12-15 CN claimed
CN-117126477-A Self-cleaning coated co-extrusion functional material, preparation method thereof and coated co-extrusion molding body 浙江豪韵塑竹木材料有限公司 2023-11-28 CN claimed
EP-3676311-B1 NOVEL (PER)FLUOROPOLYETHER POLYMERS AND USE THEREOF SOLVAY SPECIALTY POLYMERS IT (IT) 2023-10-18 EP claimed
CN-111148778-B (per) fluoropolyether polymers and use thereof 索尔维特殊聚合物意大利有限公司 2023-06-02 CN claimed
CN-112919417-A Method for producing high-purity hydrochloric acid by using fluorocarbon alkane byproduct hydrochloric acid 太仓中化环保化工有限公司 2021-06-08 CN claimed
EP-3088487-B1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2021-05-05 EP claimed
CN-107849234-B Process for the synthesis of (per) fluoropolyether amines 索尔维特殊聚合物意大利有限公司 2021-01-12 CN claimed
US-10723839-B2 Process for the synthesis of (per)fluoropolyether amines SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2020-07-28 US claimed
WO-1995000588-A1 CROSSLINKING FLUOROPOLYMER COMPOSITIONS ALLIEDSIGNAL INC. (US) 1995-01-05 WO claimed
US-5322557-A Fluorinated alkoxysilane containing an epoxy group, organic titanium or aluminum compound, and solvent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-06-21 US claimed
WO-1993024569-A1 CROSSLINKABLE FLUOROPOLYMER COMPOSITIONS ALLIED-SIGNAL INC. (US) 1993-12-09 WO claimed
US-4929753-A Preparation of trifluoromethylbenzoic acid from hexafluoroxylene CENTRAL GLASS COMPANY, LIMITED (JP) 1990-05-29 US claimed
US-4900474-A Silicone antifoamers SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-02-13 US claimed
US-4080319-A Elastomeric copolymides containing fluorine and process for preparing same MONTEDISON S.P.A. (IT) 1978-03-21 US claimed
US-4038276-A PROCESS FOR THE PRODUCTION OF FINELY DIVIDED SOLID CYANURIC CHLORIDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-07-26 US claimed
US-3961023-A Process for the production of cyanogen chloride and hydrogen chloride DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-06-01 US claimed
US-3947257-A BENZOTRIFLUORIDE FUEL ADDITIVE FOR INTERNAL COMBUSTION ENGINES RAYCHEM CORPORATION (US) 1976-03-30 US claimed
US-3931454-A Printed circuit board and method of preparing it WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-01-06 US claimed