SCHEMBL6411348

SCHEMBL6411348

Cc1c(Br)cc(C(F)(F)F)c(F)c1Br

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.32
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23658918 0.78 ADRB2 (0.39) NOTUMMAPTNPSR1
SCHEMBL4768740 0.73 NOTUM (0.32) NOTUM
SCHEMBL29560549 0.72 NOTUM (0.36) NOTUMMEN1NPC1MAPTHTT
SCHEMBL22866837 0.72 NOTUM (0.36) NOTUMMEN1NPC1MAPTHTT
SCHEMBL29596950 0.72 KIF11 (0.33) NOTUMMEN1NPC1MAPTHTT
SCHEMBL24499756 0.72 KIF11 (0.33) NOTUMMEN1NPC1MAPTHTT
SCHEMBL2954135 0.71 SOS1 (0.32) NOTUMMEN1NPC1MAPTHTT
SCHEMBL23099952 0.71 CYP11B1 (0.31)
SCHEMBL29322467 0.71 CYP11B1 (0.31)
SCHEMBL10104495 0.70 HTT (0.37) NOTUMMEN1NPC1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0549980-B1 Processes for the preparation of octafluoro-[2,2] paracyclophane SPECIALTY COATING SYSTEMS INC (US) 1996-07-24 EP claimed
US-5268202-A Using halogen promoter and metal catalyst RENSSELAER POLYTECHNIC INSTITUTE (US) 1993-12-07 US claimed
EP-0549980-A1 Processes for the preparation of octafluoro-[2,2] paracyclophane SPECIALTY COATING SYSTEMS, INC. (US) 1993-07-07 EP claimed
US-5210341-A Processes for the preparation of octafluoro-[2,2]paracyclophane UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-05-11 US claimed
US-20050047927-A1 Process modules for transport polymerization of low epsilon thin films DIELECTRIC SYSTEMS, INC. 2005-03-03 US disclosed
WO-2003089680-A2 PROCESS MODULES FOR TRANSPORT POLYMERIZATION OF LOW DIELETRIC CONSTANT THIN FILMS DIELECTRIC SYSTEMS, INC. (US) 2003-10-30 WO disclosed
US-20030198578-A1 Multi-stage-heating thermal reactor for transport polymerization DIELECTRIC SYSTEMS, INC. 2003-10-23 US disclosed
US-20030196680-A1 Process modules for transport polymerization of low epsilon thin films DIELECTRIC SYSTEMS, INC (US) 2003-10-23 US disclosed
US-6150010-A Integrated circuit insulator TEXAS INSTRUMENTS INCORPORATED (US) 2000-11-21 US disclosed
US-6086679-A Deposition systems and processes for transport polymerization and chemical vapor deposition QUESTER TECHNOLOGY, INC. (US) 2000-07-11 US disclosed
US-6030706-A Integrated circuit insulator and method TEXAS INSTRUMENTS INCORPORATED (US) 2000-02-29 US disclosed
EP-0970938-A1 Preparation of 1,4-bis-(difluoromethyl)benzene AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-01-12 EP disclosed
EP-0549980-B1 Processes for the preparation of octafluoro-[2,2] paracyclophane SPECIALTY COATING SYSTEMS INC (US) 1996-07-24 EP disclosed
US-5268202-A Using halogen promoter and metal catalyst RENSSELAER POLYTECHNIC INSTITUTE (US) 1993-12-07 US disclosed
US-5268202-A Using halogen promoter and metal catalyst RENSSELAER POLYTECHNIC INSTITUTE (US) 1993-12-07 US disclosed
EP-0549980-A1 Processes for the preparation of octafluoro-[2,2] paracyclophane SPECIALTY COATING SYSTEMS, INC. (US) 1993-07-07 EP disclosed
US-5210341-A Processes for the preparation of octafluoro-[2,2]paracyclophane UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-05-11 US disclosed
EP-0113185-B2 SELECTIVE BROMINATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-07-24 EP disclosed
EP-0113185-B1 SELECTIVE BROMINATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-09 EP disclosed
EP-0113185-A1 Selective bromination process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-07-11 EP disclosed