SCHEMBL29322917

SCHEMBL29322917

CN1CCC(OCC#Cc2cccc3c(C4CCC(=O)NC4=O)coc23)CC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.39
DDB1 Q16531 18/20 0.39
DRD2 P14416 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29322910 0.89 CRBN (0.37) CRBNDDB1
SCHEMBL29322908 0.87 DDB1 (0.47) CRBNDDB1
SCHEMBL29331542 0.86 CRBN (0.37) CRBNDDB1
SCHEMBL29322939 0.82 ALDH2 (0.36) CRBNDDB1DRD2HTR2AHTR2C
SCHEMBL29331598 0.77 DDB1 (0.38) CRBNDDB1
SCHEMBL29323433 0.75 DDB1 (0.34) CRBNDDB1
SCHEMBL25959886 0.71 CRBN (0.51) CRBNDDB1
SCHEMBL23115306 0.71 DDB1 (0.50) CRBNDDB1
SCHEMBL25861881 0.71 CRBN (0.56) CRBNDDB1
SCHEMBL29324998 0.70 CYP2C19 (0.50) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed