SCHEMBL29324998

SCHEMBL29324998

CN1CCN(CC(=O)Nc2cccc3c([C@H]4CCC(=O)NC4=O)coc23)CC1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.50
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HTT P42858 2/20 0.42
RECQL P46063 1/20 0.41
ALDH1A1 P00352 4/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
CHRM1 P11229 1/20 0.40
JAK1 P23458 1/20 0.40
POLB P06746 2/20 0.39
DDB1 Q16531 2/20 0.39
CRBN Q96SW2 2/20 0.39
MAP1LC3B Q9GZQ8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323213 0.87 DDB1 (0.49) ALDH1A1KDM4ECHRM1POLBDDB1
SCHEMBL29323451 0.87 CYP2C19 (0.48) CYP2C19MEN1KMT2AHTTRECQL
SCHEMBL29323930 0.84 CYP2C19 (0.48) CYP2C19MEN1KMT2AHTTRECQL
SCHEMBL29322788 0.81 CRBN (0.42) MEN1KMT2AALDH1A1TSHRMAPK1
SCHEMBL29318263 0.79 CYP2C19 (0.48) CYP2C19MEN1KMT2AHTTRECQL
SCHEMBL29323900 0.77 CYP2C19 (0.47) CYP2C19MEN1KMT2AHTTRECQL
SCHEMBL29323527 0.77 KDM4E (0.38) CYP2C19MEN1KMT2AALDH1A1KDM4E
SCHEMBL29321737 0.74 ALDH1A1 (0.38) CYP2C19ALDH1A1KDM4EDDB1CRBN
SCHEMBL30662928 0.73 DDB1 (0.58) CYP2C19MEN1KMT2AALDH1A1KDM4E
SCHEMBL24141401 0.73 DDB1 (0.55) CYP2C19ALDH1A1KDM4EDDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed