Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29320165 | 0.89 | XIAP (0.34) | XIAPBIRC2ALDH1A1TMEM97SIGMAR1 | |
| SCHEMBL30109126 | 0.84 | XIAP (0.41) | GAAXIAPBIRC2ALDH1A1EPHX2 | |
| SCHEMBL30109209 | 0.84 | XIAP (0.41) | GAAXIAPBIRC2ALDH1A1EPHX2 | |
| SCHEMBL31269556 | 0.84 | XIAP (0.41) | GAAXIAPBIRC2ALDH1A1EPHX2 | |
| SCHEMBL29320350 | 0.82 | ALDH1A1 (0.36) | GAAALDH1A1KDM4ELMNA | |
| SCHEMBL29324631 | 0.82 | ALDH1A1 (0.36) | SMN1; SMN2XIAPBIRC2ALDH1A1TMEM97 | |
| SCHEMBL31056475 | 0.80 | TMEM97 (0.42) | ALDH1A1TMEM97SIGMAR1KDM4ENPC1 | |
| SCHEMBL31056754 | 0.79 | HTR4 (0.34) | XIAPBIRC2ALDH1A1ADRA1AADRA1B | |
| SCHEMBL31056638 | 0.78 | CD274 (0.34) | GAASMN1; SMN2XIAPBIRC2ALDH1A1 | |
| SCHEMBL31056950 | 0.77 | PDE4B (0.40) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |