Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 5/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27391631 | 0.85 | TDP1 (0.57) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3455181 | 0.84 | MAPK14 (0.56) | MAPK14CYP2C9MAPK11MCHR1MLYCD | |
| SCHEMBL4262877 | 0.84 | MAPK14 (0.56) | MAPK14CYP2C9MAPK11MCHR1MLYCD | |
| SCHEMBL6457795 | 0.79 | KCNH2 (0.60) | CACNA1IMCHR1MLYCDHDAC6ADRA2A | |
| SCHEMBL3890983 | 0.79 | KCNH2 (0.60) | CACNA1IMCHR1MLYCDHDAC6ADRA2A | |
| SCHEMBL3890990 | 0.79 | KCNH2 (0.60) | CACNA1IMCHR1MLYCDHDAC6ADRA2A | |
| SCHEMBL5519161 | 0.77 | KAT6A (0.50) | HSD17B13 | |
| SCHEMBL5519166 | 0.77 | KAT6A (0.50) | HSD17B13 | |
| SCHEMBL5526168 | 0.76 | AR (0.45) | HSD17B13 | |
| SCHEMBL5526173 | 0.76 | AR (0.45) | HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | HSD17B13 1/4885MAPK14 2314/4885CYP2C9 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.