Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.49 |
| ▸ | DRD3 | P35462 | 14/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31245767 | 1.00 | DRD2 (0.49) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL29323478 | 0.99 | DRD2 (0.49) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL30179327 | 0.99 | DRD2 (0.49) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL30179291 | 0.87 | DRD2 (0.54) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL28967727 | 0.87 | DRD2 (0.54) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL26908463 | 0.84 | DRD2 (0.58) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL29323474 | 0.83 | DRD2 (0.52) | DRD2DRD3 | |
| SCHEMBL26908476 | 0.83 | DRD2 (0.59) | DRD2DRD3HTR1A | |
| SCHEMBL30179191 | 0.76 | DRD2 (0.56) | DRD2HTR1A | |
| SCHEMBL28967714 | 0.76 | DRD2 (0.56) | DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | disclosed |