Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 15/20 | 0.49 |
| ▸ | DRD3 | P35462 | 14/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323463 | 1.00 | DRD2 (0.49) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL29323478 | 0.99 | DRD2 (0.49) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL30179327 | 0.99 | DRD2 (0.49) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL30179291 | 0.87 | DRD2 (0.54) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL28967727 | 0.87 | DRD2 (0.54) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL26908463 | 0.84 | DRD2 (0.58) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL29323474 | 0.83 | DRD2 (0.52) | DRD2DRD3 | |
| SCHEMBL26908476 | 0.83 | DRD2 (0.59) | DRD2DRD3HTR1A | |
| SCHEMBL30179191 | 0.76 | DRD2 (0.56) | DRD2HTR1A | |
| SCHEMBL28967714 | 0.76 | DRD2 (0.56) | DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383913-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2024-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383913-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | TACR1, HTR1F, TPH1 | DRD2 52/4885DRD3 198/4885HTR1A 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.