SCHEMBL29323743

SCHEMBL29323743

C=C(C)C(=O)Oc1ccc(S(=O)(=O)Cc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.55
TSHR P16473 2/20 0.54
HSD17B10 Q99714 1/20 0.54
LMNA P02545 2/20 0.48
MAPT P10636 3/20 0.47
LTA4H P09960 1/20 0.45
KMT2A Q03164 5/20 0.42
ATM Q13315 1/20 0.42
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ALDH1A1 P00352 2/20 0.41
PKM P14618 1/20 0.41
NAMPT P43490 1/20 0.40
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
FFAR1 O14842 1/20 0.39
HSD11B1 P28845 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323749 0.82 ELANE (0.51) ELANELMNAMAPTKMT2AATM
SCHEMBL11353850 0.80 ELANE (0.51) ELANETSHRPOLBSMN1; SMN2ALDH1A1
SCHEMBL2431290 0.79 ELANE (0.64) ELANELMNALTA4HKMT2AATM
SCHEMBL29323870 0.78 ELANE (0.49) ELANEHSD17B10KMT2AATMALDH1A1
SCHEMBL29323861 0.77 ELANE (0.51) ELANEKMT2AATMPOLBSMN1; SMN2
SCHEMBL1232411 0.77 PKM (0.67) ELANELMNAMAPTKMT2AATM
SCHEMBL28062290 0.77 MAOB (0.62) ELANELMNASMN1; SMN2ALDH1A1HTT
SCHEMBL15058 0.77 ELANE (0.73) ELANEHSD17B10MAPTKMT2AATM
SCHEMBL87437 0.77 ELANE (0.73) ELANEHSD17B10MAPTKMT2AATM
Benzene SCHEMBL28301757 0.77 ELANE (0.73) ELANEHSD17B10MAPTKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed