Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323901 | 0.77 | AAK1 (0.46) | ATRAAK1CYP17A1RAB9AMETAP1 | |
| SCHEMBL21339691 | 0.77 | ATR (0.42) | ATRABL1METAP1BRD9KDM4E | |
| SCHEMBL23500611 | 0.77 | ATR (0.42) | ATRAAK1CYP17A1METAP1BRD9 | |
| SCHEMBL30118372 | 0.76 | AAK1 (0.48) | PORCNABL1AAK1CYP17A1HDAC3 | |
| SCHEMBL29060089 | 0.75 | RXFP1 (0.44) | ATRRAB9AMETAP1KDM4EHTT | |
| SCHEMBL27039833 | 0.74 | PORCN (0.50) | PORCNABL1AAK1TGFBR1 | |
| SCHEMBL6365954 | 0.72 | ALDH1A1 (0.45) | RAB9ANAMPTMETAP1BRD9KDM4E | |
| SCHEMBL20911219 | 0.72 | NAMPT (0.46) | CYP17A1NAMPT | |
| SCHEMBL4345991 | 0.71 | METAP1 (0.62) | ATRCYP17A1RAB9ANAMPTMETAP1 | |
| SCHEMBL29686286 | 0.71 | TYK2 (0.39) | ATRAAK1CYP17A1NAMPTMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |