Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 3/20 | 0.45 |
| ▸ | CSF1R | P07333 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21377439 | 0.89 | CSF1R (0.53) | CYP2C19KITCSF1RLCKPGR | |
| SCHEMBL1743280 | 0.85 | TKT (0.39) | RAB9ANPC1 | |
| SCHEMBL29324033 | 0.80 | CYP2C19 (0.40) | CYP2C19KITCSF1RLCKPGR | |
| SCHEMBL24594026 | 0.77 | CYP2C19 (0.56) | CYP2C19KITCSF1RLCKPGR | |
| SCHEMBL21377437 | 0.76 | CSF1R (0.53) | CYP2C19KITCSF1RLCKPGR | |
| SCHEMBL22663449 | 0.76 | KDM1A (0.40) | CYP2C19KITCSF1RLCKPGR | |
| SCHEMBL28783425 | 0.74 | KDM1A (0.45) | CYP2C19KITCSF1RLCKPGR | |
| SCHEMBL2599920 | 0.73 | NPC1 (0.52) | CYP2C19KITCSF1RLCKPGR | |
| SCHEMBL26326733 | 0.73 | NPC1 (0.52) | CYP2C19KITCSF1RLCKPGR | |
| SCHEMBL28647391 | 0.72 | HCAR3 (0.52) | CYP2C19KITCSF1RLCKPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239793-A1 | PROCESS FOR PREPARING PEXIDARTINIB | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239793-A1 | PROCESS FOR PREPARING PEXIDARTINIB | F9, FLT3, F12 | CYP2C19 29/4885KIT 53/4885CSF1R 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.