Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 3/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323913 | 0.78 | RORC (0.33) | RORC | |
| SCHEMBL23500611 | 0.73 | ATR (0.42) | ATRMETAP1RORCGSK3BDYRK1A | |
| SCHEMBL29323901 | 0.73 | AAK1 (0.46) | ATRMETAP1RECQLRORCGSK3B | |
| SCHEMBL21339691 | 0.73 | ATR (0.42) | ATRMETAP1GSK3BDYRK1A | |
| SCHEMBL29060089 | 0.71 | RXFP1 (0.44) | ATRMETAP1 | |
| SCHEMBL29323903 | 0.67 | ATR (0.40) | ATRMETAP1 | |
| SCHEMBL26071946 | 0.66 | ATR (0.42) | ATR | |
| SCHEMBL29812170 | 0.66 | ATR (0.42) | ATR | |
| SCHEMBL4345991 | 0.65 | METAP1 (0.62) | ATRMETAP1 | |
| SCHEMBL12583021 | 0.65 | ATR (0.43) | ATRMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |