Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 7/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18935522 | 0.74 | MTNR1A (0.51) | BRD4MTNR1AMTNR1B | |
| SCHEMBL29657293 | 0.74 | NQO2 (0.53) | PLK1BRD4MTNR1AMTNR1B | |
| SCHEMBL24453122 | 0.74 | NQO2 (0.53) | PLK1BRD4MTNR1AMTNR1B | |
| SCHEMBL3417837 | 0.74 | MTNR1A (0.50) | BRD4MTNR1AMTNR1B | |
| SCHEMBL849609 | 0.74 | HDAC10 (0.44) | DRD2CNR2SCN9A | |
| SCHEMBL7671707 | 0.74 | KMO (0.54) | BRD4DRD2MTNR1AMTNR1B | |
| SCHEMBL24476972 | 0.73 | BUB1 (0.42) | PLK1NR3C1PGRNR3C2 | |
| SCHEMBL28649216 | 0.73 | HDAC6 (0.50) | PLK1 | |
| SCHEMBL27759313 | 0.73 | PLK1 (0.38) | PLK1BRD4DRD2CNR2SCN9A | |
| SCHEMBL23116611 | 0.72 | MAPK1 (0.67) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | disclosed |