Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959780 | 0.77 | HTR2C (0.59) | HTR6CDK4CCND1HTR2AHTR2C | |
| SCHEMBL10627404 | 0.75 | KDM4E (0.51) | GSK3BPLK1MEN1POLBKMT2A | |
| SCHEMBL5316613 | 0.74 | MAPT (0.47) | HTR6MEN1POLBKMT2A | |
| SCHEMBL28651148 | 0.73 | HTR2C (0.59) | CDK4CCND1HTR2AHTR2C | |
| SCHEMBL21863275 | 0.73 | KDM4E (0.43) | CDK4CCND1POLBKMT2AHTR2A | |
| SCHEMBL8959699 | 0.72 | HTR2A (0.63) | HTR6ICMTHTR2AHTR2C | |
| SCHEMBL29324199 | 0.71 | PLK1 (0.46) | PLK1NR3C1PGRNR3C2 | |
| Fumaric Acid SCHEMBL8959697 | 0.70 | HTR2A (0.48) | HTR6CDK4CCND1HTR2AHTR2C | |
| Fumaric Acid SCHEMBL8959686 | 0.70 | HTR2A (0.48) | HTR6CDK4CCND1HTR2AHTR2C | |
| SCHEMBL21848998 | 0.70 | RORA (0.48) | NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | disclosed |