SCHEMBL29324307

SCHEMBL29324307

CC(C)(C)OC(=O)NCCn1cc(C(=O)O)c(=O)c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
CHRM1 P11229 3/20 0.51
CAMK2D Q13557 2/20 0.49
CNR2 P34972 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324305 0.87 CNR1 (0.48) LMNACAMK2DCNR2
SCHEMBL9319939 0.83 ALDH1A1 (0.42) LMNACAMK2D
SCHEMBL9354163 0.81 CAMK2D (0.49) LMNACAMK2DCNR2
SCHEMBL29443972 0.80 MAPT (0.45) LMNACAMK2D
SCHEMBL2013170 0.80 CYP19A1 (0.57) LMNACAMK2DCNR2
SCHEMBL29324351 0.79 ALDH1A1 (0.62) LMNA
SCHEMBL6073363 0.79 CAMK2D (0.51) CAMK2DCNR2
SCHEMBL6073315 0.78 CAMK2D (0.42) CAMK2DCNR2
SCHEMBL4176799 0.77 ALDH1A1 (0.43) CAMK2DCNR2
SCHEMBL6073784 0.77 CAMK2D (0.42) CAMK2DCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151425-A1 COMPOUNDS AND METHOD FOR TREATING HIV INFECTION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-07-18 WO disclosed