Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25087455 | 0.95 | CTSK (0.45) | CTSKSLC6A2SLC6A4KCNH2MGLL | |
| SCHEMBL27226089 | 0.84 | HRH1 (0.44) | CTSKSLC6A2SLC6A4KCNH2MGLL | |
| SCHEMBL3613521 | 0.82 | HRH3 (0.55) | CTSKSLC6A2SLC6A4KCNH2MGLL | |
| SCHEMBL31546854 | 0.79 | FFAR4 (0.38) | SLC6A2SLC6A4KCNH2FFAR4BRD4 | |
| SCHEMBL3602567 | 0.78 | MGLL (0.55) | KCNH2MGLLFFAR4HRH3 | |
| SCHEMBL4442024 | 0.77 | HRH3 (0.49) | MGLLHRH3 | |
| SCHEMBL31546824 | 0.75 | FFAR4 (0.36) | SLC6A2SLC6A4KCNH2FFAR4BRD4 | |
| SCHEMBL31581118 | 0.75 | MCHR1 (0.42) | SLC6A2SLC6A4KCNH2FFAR4BRD4 | |
| SCHEMBL2144242 | 0.75 | MCHR1 (0.56) | SLC6A2SLC6A4KCNH2FFAR4BRD4 | |
| SCHEMBL958367 | 0.75 | MCHR1 (0.45) | SLC6A2SLC6A4KCNH2FFAR4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239797-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239797-A1 | AKT1 MODULATORS | AKT1S1, AKT1, AKT2 | CTSK 2726/4885SLC6A2 4281/4885SLC6A4 4124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.