Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10309642 | 0.83 | ALDH1A1 (0.53) | ALDH1A1BRD4CREBBPEP300 | |
| SCHEMBL8402252 | 0.80 | MMP12 (0.41) | DDB1CRBNALDH1A1BRD4CREBBP | |
| SCHEMBL1347194 | 0.78 | DDB1 (0.49) | DDB1CRBNNPC1MAPK13MAPK12 | |
| SCHEMBL9278082 | 0.78 | ALDH1A1 (0.38) | DDB1CRBNNPC1MAPK13MAPK12 | |
| SCHEMBL9405618 | 0.75 | NPC1 (0.47) | DDB1CRBNNPC1MAPK13MAPK12 | |
| SCHEMBL9405619 | 0.75 | NPC1 (0.47) | DDB1CRBNNPC1MAPK13MAPK12 | |
| SCHEMBL8524142 | 0.74 | CRBN (0.46) | DDB1CRBNNPC1MAPK13MAPK12 | |
| SCHEMBL29960465 | 0.74 | CRBN (0.40) | DDB1CRBNNPC1MAPK13MAPK12 | |
| SCHEMBL8921290 | 0.73 | MAPT (0.44) | DDB1CRBNNPC1MAPK13MAPK12 | |
| SCHEMBL24090522 | 0.73 | AR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | ASIA VISION LIMITED (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | ASIA VISION LIMITED (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239792-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | BCL2, BCL2L2, BCL2L1 | DDB1 979/4885CRBN 854/4885NPC1 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.