SCHEMBL29323900

SCHEMBL29323900

CN1CCN(CC(=O)Nc2cccc3c2ccc2onc(C4CCC(=O)NC4=O)c23)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.47
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 3/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
JAK1 P23458 1/20 0.39
DDB1 Q16531 3/20 0.38
CRBN Q96SW2 3/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
RECQL P46063 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
CHRM1 P11229 1/20 0.36
CCNE2 O96020 2/20 0.36
CDK4 P11802 2/20 0.36
CCND1 P24385 2/20 0.36
CCNE1 P24864 2/20 0.36
CDK2 P24941 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323894 0.88 DDB1 (0.48) CYP2C19ALDH1A1KDM4EDDB1CRBN
SCHEMBL29323930 0.86 CYP2C19 (0.48) CYP2C19TSHRMAPK1ALDH1A1KDM4E
SCHEMBL29323451 0.85 CYP2C19 (0.48) CYP2C19TSHRMAPK1ALDH1A1KDM4E
SCHEMBL24754173 0.81 DDB1 (0.36) ALDH1A1MEN1KMT2ADDB1CRBN
SCHEMBL24754436 0.80 DDB1 (0.34) ALDH1A1MEN1KMT2ADDB1CRBN
SCHEMBL24754291 0.79 DDB1 (0.42) DDB1CRBN
SCHEMBL29318263 0.79 CYP2C19 (0.48) CYP2C19TSHRMAPK1ALDH1A1KDM4E
SCHEMBL29324998 0.77 CYP2C19 (0.50) CYP2C19TSHRMAPK1ALDH1A1KDM4E
SCHEMBL29323657 0.77 CRBN (0.40) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL29321737 0.77 ALDH1A1 (0.38) CYP2C19ALDH1A1KDM4EDDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed