SCHEMBL29323213

SCHEMBL29323213

CC(C)(C)OC(=O)N1CCN(CC(=O)Nc2cccc3c(C4CCC(=O)NC4=O)coc23)CC1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 12/20 0.49
CRBN Q96SW2 12/20 0.49
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
POLB P06746 1/20 0.38
CETP P11597 1/20 0.38
PARP1 P09874 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323524 0.88 DDB1 (0.46) DDB1CRBNCHRM2CHRM4CHRM1
SCHEMBL29324998 0.87 CYP2C19 (0.50) DDB1CRBNCHRM1POLBKDM4E
SCHEMBL29321735 0.86 DDB1 (0.48) DDB1CRBNCHRM2CHRM4CHRM1
SCHEMBL29322766 0.84 DDB1 (0.48) DDB1CRBNCETPKDM4EALDH1A1
SCHEMBL29322819 0.84 DDB1 (0.50) DDB1CRBNCETPKDM4EALDH1A1
SCHEMBL29324152 0.84 DDB1 (0.49) DDB1CRBNKDM4E
SCHEMBL31444707 0.81 DDB1 (0.57) DDB1CRBNCHRM2CHRM4CHRM1
SCHEMBL29323894 0.80 DDB1 (0.48) DDB1CRBNCHRM2CHRM4CHRM1
SCHEMBL29323374 0.79 DDB1 (0.47) DDB1CRBNCETPKDM4EALDH1A1
SCHEMBL29322908 0.76 DDB1 (0.47) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed