Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAP2 | P11137 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326663 | 0.91 | HSD17B10 (0.41) | ERCC5FEN1ADRA1BCYP1A2HSD17B10 | |
| SCHEMBL27377457 | 0.90 | P2RX7 (0.33) | ERCC5FEN1ADRA1DADRA1AADRA1B | |
| SCHEMBL29326658 | 0.86 | ERCC5 (0.39) | ERCC5FEN1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL29326200 | 0.84 | CYP1A1 (0.43) | ERCC5FEN1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL29326188 | 0.81 | CYP1A1 (0.53) | ERCC5FEN1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL27379207 | 0.81 | CDK2 (0.40) | HSD17B10PKMCYP3A4CYP2C9KDM4E | |
| SCHEMBL29326183 | 0.79 | ERCC5 (0.43) | ERCC5FEN1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL29326179 | 0.78 | ERCC5 (0.41) | ERCC5FEN1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL29326210 | 0.78 | ERCC5 (0.40) | ERCC5FEN1ADRA1BMAPTHTT | |
| SCHEMBL29326166 | 0.77 | ERCC5 (0.60) | ERCC5FEN1ADRA1BCYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | ERCC5 2042/4885FEN1 1012/4885ADRA1D 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.