Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377463 | 0.89 | CDK2 (0.41) | ALDH1A1MAPTKDM4EGSK3BCDK2 | |
| SCHEMBL29326183 | 0.84 | ERCC5 (0.43) | ALDH1A1MAPTKDM4EGSK3BERCC5 | |
| SCHEMBL29326302 | 0.82 | NPEPPS (0.43) | ALDH1A1MAPTKDM4EFEN1TDP1 | |
| SCHEMBL29326162 | 0.82 | CYP1A1 (0.53) | ALDH1A1KDM4EGSK3BERCC5FEN1 | |
| SCHEMBL29326188 | 0.82 | CYP1A1 (0.53) | ALDH1A1KDM4EGSK3BERCC5FEN1 | |
| SCHEMBL29326210 | 0.81 | ERCC5 (0.40) | ALDH1A1MAPTKDM4EERCC5FEN1 | |
| SCHEMBL29326194 | 0.80 | ERCC5 (0.40) | ALDH1A1KDM4EGSK3BERCC5FEN1 | |
| SCHEMBL29326196 | 0.80 | CYP1A1 (0.44) | ALDH1A1KDM4EGSK3BERCC5FEN1 | |
| SCHEMBL29326166 | 0.80 | ERCC5 (0.60) | ALDH1A1KDM4EGSK3BERCC5FEN1 | |
| SCHEMBL29326215 | 0.80 | ERCC5 (0.41) | ALDH1A1KDM4EGSK3BERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | ALDH1A1 3259/4885MAPT 2197/4885KDM4E 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.