Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27378012 | 0.89 | METAP2 (0.41) | IDO1METAP2DHODHNPEPPSPRMT5 | |
| SCHEMBL29326246 | 0.89 | METAP2 (0.43) | IDO1ITGA4ITGB7METAP2NPEPPS | |
| SCHEMBL29326236 | 0.86 | NPEPPS (0.44) | ITGA4ITGB7NPEPPSFEN1HCAR1 | |
| SCHEMBL29326224 | 0.86 | NPEPPS (0.48) | ITGA4ITGB7NPEPPSFEN1HCAR1 | |
| SCHEMBL29326326 | 0.85 | PRMT5 (0.43) | IDO1ITGA4ITGB7METAP2NPEPPS | |
| SCHEMBL29326219 | 0.82 | ERCC5 (0.42) | IDO1ITGA4ITGB7DHODHNPEPPS | |
| SCHEMBL29326363 | 0.82 | TNKS2 (0.50) | ITGA4ITGB7NPEPPSFEN1TNKS2 | |
| SCHEMBL29326290 | 0.81 | NPEPPS (0.42) | ITGA4ITGB7NPEPPSFEN1HCAR1 | |
| SCHEMBL29326225 | 0.81 | NPEPPS (0.48) | NPEPPSFEN1HCAR1TNKS2TDP1 | |
| SCHEMBL27380572 | 0.81 | PTGES (0.40) | NPEPPSTNKS2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | IDO1 1204/4885ITGA4 4792/4885ITGB7 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.